For the Management of
MTX Toxicity

AUTHORISED UNDER EXCEPTIONAL CIRCUMSTANCES

Exceptional Circumstances means that due to the rarity of the disease and for ethical reasons it has not been possible to obtain complete information on this medicinal
product. The European Medicine Agency will review any new information which may become available every year and this
Summary of Product Characteristics (SmPC) will be updated as necessary.

Voraxaze® is indicated to reduce toxic plasma methotrexate concentration in adults and children (aged 28 days and older) with delayed methotrexate elimination.4
This medicinal product is subject to additional monitoring. Healthcare professionals are asked to report any suspected adverse reactions.

Why Stock Voraxaze
Voraxaze lowers plasma MTX 
by >98% in 15 minutes.4
View Efficacy
High-Dose Methotrexate (HDMTX) Toxicity and Acute Kidney Injury
Keep Voraxaze top-of-mind when treating with HDMTX.
Learn About HDMTX Toxicity
Identify and Treat Delayed MTX Clearance Early
Consensus Guidelines recommend early use of Voraxaze.2
View Guidelines