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UK-VRX-2600029 Date of Last Revision: February 2026

Use in Cancer
Treatment

High dose methotrexate (HDMTX)

+

HDMTX - induced nephrotoxicity

+

Delayed MTX elimination

+

Risk of systemic toxicities

+

Abbreviations: HDMTX, high dose methotrexate; MTX, methotrexate.

UK-VRX-2600031 Date of Last Revision: February 2026